Massively parallel sequencing and other high-throughput methodologies enable detailed mapping of the genomic and transcriptomic changes that underlie the development of cancer and other diseases. Rapid accumulation of genetic information in the public domain makes it increasingly feasible to test biological hypotheses using computational methods and available data.
We are tackling a variety of challenges in computational cancer genomics, with emphasis on somatic mutations and mutational processes, in particular in non-coding DNA regions. We regularly collaborate with experimental groups, locally and elsewhere, and also have a wet laboratory to complement the bioinformatics. Our research interests also include the development of bioinformatical tools to facilitate analysis of large-scale genomics data, as well as the role of viruses in human cancer.
We are located at the Institute of Biomedicine, University of Gothenburg, Sweden.